Posts by The Simonator


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1) Message boards : Politics : The reassertion of whiteness in Canada (Message 1590641)
Posted 1 day ago by Profile The Simonator
BBC News

I could've tried asking for a white taxi driver when i lived in Birmingham, but i'd end up waiting months for them to find one.
2) Message boards : Politics : Is conflict needed for human advancement? (Message 1590623)
Posted 1 day ago by Profile The Simonator
Can be James, but this guy really exists and evetho they didn't grant his wishes, he had them.

Given that the story appeared on Nordpresse, a satirical website written by Vincent Flibustier, i think it very unlikely that he exists.
3) Message boards : Politics : Ebola and Infectious diseases (Message 1589704)
Posted 2 days ago by Profile The Simonator
I'd be surprised if no one is working on a way to mass produce larger quantities of this experimental serum as we speak.

The reason they ran out is quite simply that it was an experimental serum, complicated to make and, at the time, untested.
Laboratory conditions are only useful for manufacturing very small quantities of substances (maybe up to gram scale) . Working out how to produce things on a larger scale (kilograms) takes time, as laboratory equipment doesn't scale very well.

The anti-fungal drugs i work with are an example.
Normally i produce small quantities, as biological tests only require a few milligrams.
Now, let's say there's an outbreak of a disease that one of my experimental drugs (i'll call it NK134) has been shown to be effective against. 2000 people are affected by this disease.
The IC50 of NK134 is 1.4 mg/kg. So an 80 kg human would require 112 mg to treat them.
I have (i've checked) 51 mg of NK134 in the freezer. Less than half the amount required to treat a person.
It took me 7 months to develop this drug, through the various stages of testing, modification and refinement necessary.
My final variant, takes minimum 11 days from starting materials to pure product. In that run, i produced 60 mg.
The equipment in my lab could probably produce around three times this amount in one process, so i could make 180 mg in 11 days.
Or, simply put, enough to cure 1 person a week.

Those 2000 people are going to take some time.
4) Message boards : Politics : Society's Role in Education (Message 1589701)
Posted 2 days ago by Profile The Simonator
It appears that such schooling works for those people who want to learn. They will thrive.

Those who don't want to learn won't thrive. But then those same people don't do too well in the normal education system either.
Sure, it might beat the ability to read and write into them, just. But if they don't want to succeed in exams and such they won't, and don't.
5) Message boards : Politics : Society's Role in Education (Message 1589686)
Posted 3 days ago by Profile The Simonator
Sounds like it worked for Brian keating and Martin Christie
6) Message boards : Politics : Climate Change, 'Greenhouse' effects: DENIAL (#3) (Message 1589226)
Posted 4 days ago by Profile The Simonator
i read his comments as a sarcastic response to the weather getting colder


You Sir may be very dangerous.....



What do you mean 'may'?

7) Message boards : Politics : Society's Role in Education (Message 1589225)
Posted 4 days ago by Profile The Simonator
Well she's not taking a child out of school is she...

While she may not be technically doing anything wrong, i can see why it would go down badly with the parents of children at that school who can't do it, and she should have foreseen this.

It might take a little coordination, but i think it would be funny if most or all of the parents at that school also arranged a holiday during that same week (doesn't necessarily have to be to the Caribbean, the timing is the important thing), if/when the school issues fines, then all refuse to pay (strength in numbers).
What's the school going to do, prosecute all of them? (Unworkable.)
8) Message boards : Politics : Are scientists crooked? (Message 1589224)
Posted 4 days ago by Profile The Simonator
While i wouldn't use such strong words as Jim, i must also disagree with our Dutch friend.

Scientists who stick to their pet theories after they've been proven wrong tend to lose credibility quite quickly, and with that credibility goes their likelihood of having their papers published, and without that one is no longer really a scientist.
9) Message boards : Politics : Cannabis use & Smoking (Message 1588285)
Posted 6 days ago by Profile The Simonator
That did raise a giggle.
10) Message boards : Politics : Cannabis use & Smoking (Message 1588272)
Posted 6 days ago by Profile The Simonator
Or i could beat myself over the head with a paddle and get much the same response.

MPs don't like having their opinions challenged, and drugs have had so much propaganda as life-destroying evil things that must be eradicated, they won't back down now.
11) Message boards : Politics : Tesco's latest PR blurb (Message 1588268)
Posted 6 days ago by Profile The Simonator
Tesco Guide Dogs

How's this for first class PR?

There's an echo in here.
12) Message boards : Politics : Middle East Timebomb (Message 1588265)
Posted 6 days ago by Profile The Simonator
Next escalation

Looks like we'll have to build that wall a lot higher!

The service ceiling on a MIG 21 i believe is about 55,000 feet.
13) Message boards : Politics : Cannabis use & Smoking (Message 1588256)
Posted 7 days ago by Profile The Simonator
Supply the stuff legally, with accepted minimum quality levels, and you cut down on the associated crime.

Organised crime in the supply chain maybe yes, but NOT petty crime to fund peoples personal habits. I can't supply figures, although I am sure that there are some if I searched hard enough, but I would suggest that not all Class A and hard drug users can comfortably afford their addiction. They will likely steal to fund it or beg.

Here is case in point. There is a local park, and quite often you will see some bedraggled and unkempt guy in his twenties skulking behind the gates. An equally scruffy woman walks up and down the road accosting passers by for money saying she has broken down in her car and needs to get home to her kids, or some such story. If she gets enough, there is a phone call from the local telephone box, and 5 minutes later a beat up old car arrives outside the park, with Asians in it, and things change hands. The pair of them then shuffle off up the road to god knows where.

They have been reported to the police many times (just once by me) and they get moved on, yet they are still around for about 2 years now. He is obviously on the heavy stuff and uses his girlfriend to beg to fund it. How do you deal with that then?

You're still using an illegal supplier as a comparison point.

If the stuff were available in shops; the price would probably be lower (i said probably), there would be less harmful substances mixed with it (drain cleaner, sodium bicarbonate, brick dust, who knows) and the purity would be higher so less would be needed overall. Plus, one could supply clean needles or whatever paraphernalia is necessary thus reducing secondary infections and other complications.
14) Message boards : Politics : Climate Change, 'Greenhouse' effects: DENIAL (#3) (Message 1588251)
Posted 7 days ago by Profile The Simonator
You have to look at it on a bigger scale Ian, it affects us all, our grand and grand grand children and so forth...

Nothing you can do in your current life but HELL So mote be it!

Maybe it's me, but i read his comments as a sarcastic response to the weather getting colder.

I hear it often at this time of year. People arrive in the lab bound up shivering in duffel coats decrying the lack of global warming. Not to be taken seriously.
15) Message boards : Politics : Cannabis use & Smoking (Message 1588250)
Posted 7 days ago by Profile The Simonator
Well, if it wasn't available everywhere you wouldn't get your hands on it.

That is not a realistic comment. There will always be a black market and under the counter dealings for any commodity that there is a demand for, whether it is in short supply or illegal. It ranges from drugs to guns to almost anything you want to name. If it can be produced it will be. It would be physically impossible to wipe out and destroy every type of Cannabis plant in the world, such that it never grew again. If people want heroin or cocaine, or LSD etc it will always be available at a price, just maybe a bit more difficult to get hold of at times. How do you think that the Continent of South America funds it's existence?

That's true, and banning something often leads to the creation of a black market for it, with all associated risks such as adulteration, extortion, theft, etc.
Supply the stuff legally, with accepted minimum quality levels, and you cut down on the associated crime.
16) Message boards : Politics : 7: The Torch is Lit (Message 1587811)
Posted 7 days ago by Profile The Simonator
Surely someone expected to deal with an obesity crisis should have some experience of obesity.

Otherwise it'd be like employing a chancellor who couldn't count...okay, bad example.
A health minister who believed in homeopathy...nope, wrong again.
17) Message boards : Politics : Cannabis use & Smoking (Message 1587189)
Posted 8 days ago by Profile The Simonator
The tabloid press are all over this, as you would expect. They couldn't give a monkeys that it costs the NHS £5 Billion a year to treat smoking induced diseases, all they want to do is to stir up the debate to sell more newspapers.

And the government rakes in £9.7 billion p.a. in tobacco duty plus another £2.6 billion from the VAT. Total: £12.3 billion.
12.3 - 5 = £7.3 billion left over.
I think the NHS can easily afford to treat them.

(figures)
18) Message boards : Politics : Cannabis use & Smoking (Message 1587187)
Posted 8 days ago by Profile The Simonator
There was a time when this was a free country...

Oh please don't be so melodramatic.

If you wished you could go to Hyde park Corner in London, and wear a placard that proclaimed "Down with the Government!". Provided that you were not causing a public affray or disturbance, you would be "free" to do so. Now, go try doing that in North Korea, China, Russia, or any typical Eastern European country, and see how quickly you get imprisoned for a crime against the State. Oh, and we might add South America and a lot of Africa to that list as well.

The UK probably has more Civil Liberty than any Western world country, but if you are unhappy living here, and think that there is somewhere else that would be better for you, then you know where the port of Dover is, and we wish you Bon Voyage! You come across like an ex left wing student with a chip on their shoulder against the establishment, if that is not the case and you would like to change things for what you would see as the better, then lets hear some proposals.

That things are worse elsewhere is not an excuse for eroding civil liberties here.

I want the Government to stick to fixing roads, making the trains run on time, catching criminals, and other such administrative duties.

What i object to is them micromanaging every aspect of our lives, don't do this, don't do that...
Lets stick to big things like don't knife people or do 130 mph past a primary school after drinking a bottle of scotch.
When they get down to nitty things like what i want to put into my own body, that should be up to me and no-one else.

I wouldn't say we don't need a government, that would be ridiculous.
I would say we don't need as much government.
But this is getting off topic.

In the meantime the Surgeon General and the government have come up with some suggestions as to the way forward regarding smoking, and safeguarding the nations health, which is their responsibility to do.
They're welcome to suggest that people should smoke less.
When they start bringing in laws prohibiting stuff, that is beyond suggesting, that is curbing freedom.

Next they'll be "suggesting" that people don't leave their house at night to reduce public disturbances; then bam, curfews.

I'm worried about this being the thin end of the wedge.
19) Message boards : Politics : Climate Change, 'Greenhouse' effects: Solutions #2 (Message 1587114)
Posted 8 days ago by Profile The Simonator
Simon you do realize you said that in a public place and now anybody that stays at you place is going to ask you to disinfect the shower and insist they shower first .

People that prudish aren't invited to my house.
20) Message boards : Politics : Society's Role in Education (Message 1587112)
Posted 8 days ago by Profile The Simonator
realise that if you want to play with the big boys and be in government, it often means taking unpopular decisions, and at times these decisions can come back to haunt you. Name of the game old son.
No. If you make promises, keep them, or people won't trust you in the future.
Never mind the "government is a tough job" excuses.
Clegg pledged to do one thing, and then did another. That is (simply put) a lie, or another way to put it is an abuse of trust. We students (i was one at the time) trusted Clegg to keep his word, he then broke that word, ergo we won't trust him again (at least I won't).

but the Lib Dems knew full well that they had a pre-election promise not to raise student fees.
Clegg must be a fairly clever man to have made it to where he is, but if he didn't see that breaking his word over such a clearly defined issue would overshadow all the 'good' he's done, then he's not a very sharp politician.


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