MRNA Vaccine Fights Deadly Brain Tumor in Small Trial

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Message 2135419 - Posted: 3 May 2024, 0:51:46 UTC

MRNA Vaccine Fights Deadly Brain Tumor in Small Trial

Key Takeaways

  • An experimental vaccine can help a person’s body fight an aggressive form of brain tumor

  • The vaccine is made personally for each patient, using genetic material drawn from their own tumor

  • It activated the immune system against brain tumors in human, dog and mouse studies


One of the most impressive results was how quickly the injectable vaccine turns the immune system against a brain tumor, said senior researcher Dr. Elias Sayour, a pediatric oncologist with University of Florida Health who pioneered the new vaccine.

In a first-ever human clinical trial with four adult patients, the vaccine prompted a quick and apparently effective immune attack on cancer.

“In less than 48 hours, we could see these tumors shifting from what we refer to as ‘cold’ -- immune cold, very few immune cells, very silenced immune response -- to ‘hot,’ very active immune response,” Sayour said in a university news release.
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Message boards : Science (non-SETI) : MRNA Vaccine Fights Deadly Brain Tumor in Small Trial


 
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