Ebola and Infectious diseases Part Two

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Message 1591010 - Posted: 23 Oct 2014, 22:43:32 UTC - in response to Message 1591008.  
Last modified: 23 Oct 2014, 22:44:26 UTC

Possible new case.

Doctor who treated Ebola patients is rushed to NYC hospital

The Big Apple may have its first case of Ebola.

A 33-year-old Doctors Without Borders physician who recently treated Ebola patients in Guinea was rushed in an ambulance with police escorts from his Harlem home to Bellevue Hospital on Thursday, sources said.

Craig Spencer was suffering from Ebola-like symptoms — a 103-degree fever and nausea, sources said.

He landed at JFK airport on Oct. 17 on a connecting flight from Brussels, a source said. Spencer’s temperature was 98.7 degrees upon arrival, the source added.

Girlfriend quarantined...

http://nypost.com/2014/10/23/nyc-may-have-its-first-ebola-case/



I saw that about 3 hours ago... They should have the initial test results back on him in about 8 or 9 hours.

I must wonder, though, why they removed the door from his apartment building...


I did not see his door removed on CNN. Must look closer tonight.
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Message 1591011 - Posted: 23 Oct 2014, 22:45:29 UTC - in response to Message 1591010.  

Ebola crisis: Mali confirms first infection case

The Malian government has confirmed the first case of Ebola in the country.

It said a two-year-old girl had tested positive for the haemorrhagic virus. Reports say she recently returned from the neighbouring Guinea.

More than 4,800 people have died of Ebola - mainly in Liberia, Guinea and Sierra Leone - since March.

Meanwhile, an international team of scientists has been set up to determine the effectiveness of using the blood of Ebola survivors as a treatment.

http://www.bbc.com/news/world-africa-29750723
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Message 1591030 - Posted: 23 Oct 2014, 23:10:04 UTC - in response to Message 1591010.  




I saw that about 3 hours ago... They should have the initial test results back on him in about 8 or 9 hours.

I must wonder, though, why they removed the door from his apartment building...


I did not see his door removed on CNN. Must look closer tonight.


Nevermind. I just saw an update to the story I saw first. They now said WHY they took the door off.

http://www.nydailynews.com/new-york/doctor-treated-ebola-patients-rushed-bellevue-fever-article-1.1984941

Robert Cedano, the super in Spencer’s building, said firefighters took the doctor’s door off its hinges when they took him out of the apartment.


They put that text in place of the original question about it, and also removed the photo of the removed door they had.
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Message 1591039 - Posted: 23 Oct 2014, 23:19:16 UTC - in response to Message 1591030.  




I saw that about 3 hours ago... They should have the initial test results back on him in about 8 or 9 hours.

I must wonder, though, why they removed the door from his apartment building...


I did not see his door removed on CNN. Must look closer tonight.


Nevermind. I just saw an update to the story I saw first. They now said WHY they took the door off.

http://www.nydailynews.com/new-york/doctor-treated-ebola-patients-rushed-bellevue-fever-article-1.1984941

Robert Cedano, the super in Spencer’s building, said firefighters took the doctor’s door off its hinges when they took him out of the apartment.


They put that text in place of the original question about it, and also removed the photo of the removed door they had.



At noon Thursday, FDNY hazardous materials specialists sealed-off Spencer's apartment on W. 147th St. and took the doctor out on a stretcher.
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Message 1591048 - Posted: 23 Oct 2014, 23:40:32 UTC - in response to Message 1591039.  

Yale researchers say West African Ebola will explode

While U.S. officials scramble to curb the spread of Ebola in the U.S., the disease's epidemic spread in West Africa will likely get far worse unless international commitments are immediately increased, according to a new study led by Yale researchers.

http://www.ctpost.com/local/article/Yale-researchers-say-West-African-Ebola-will-5843529.php

If they had the vaccine back then, see it getting shelved, nobody expected this.
No one cared back then, why invest in a cure when nothing might happen.
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Message 1591064 - Posted: 24 Oct 2014, 0:23:05 UTC - in response to Message 1590998.  

You all are gonna love this... Its behind a paywall, so i'll copy-paste as much as I can...

http://www.nytimes.com/2014/10/24/health/without-lucrative-market-potential-ebola-vaccine-was-shelved-for-years.html?hp&action=click&pgtype=Homepage&version=LedeSum&module=first-column-region&region=top-news&WT.nav=top-news&_r=0&gwh=3E4FC30FAD8A3243C63A3CA2DBA94BEC&gwt=pay&assetType=nyt_now

GALVESTON, Tex. — Almost a decade ago, scientists from Canada and the United States reported that they had created a vaccine that was 100 percent effective in protecting monkeys against the Ebola virus. The results were published in a respected journal, and health officials called them exciting. The researchers said tests in people might start within two years, and a product could potentially be ready for licensing by 2010 or 2011.

It never happened. The vaccine sat on a shelf. Only now, with nearly 5,000 people dead from Ebola and an epidemic raging out of control in West Africa, is the vaccine undergoing the most basic safety tests in humans.

Its development stalled in part because Ebola was rare, and until now outbreaks had infected only a few hundred people at a time. But experts also acknowledge that the lack of follow-up on such a promising candidate reflects a broader failure to produce medicines and vaccines for diseases that afflict poor countries. Most drug companies have resisted spending the enormous sums needed to to develop products useful mostly to poor countries with little ability to pay for them.

Now, as the growing epidemic devastates West Africa and is seen as a potential threat to other regions as well, governments and aid groups have begun to open their wallets. A flurry of research to test drugs and vaccines is underway, with clinical trials starting for several candidates, including the vaccine produced nearly a decade ago. With no vaccines or proven drugs currently available, the stepped up efforts are a desperate measure to stop a disease that has defied traditional means of containing it.

“There’s never been a big market for Ebola vaccines,” said Thomas W. Geisbert, an Ebola expert here at the University of Texas Medical Branch in Galveston, and one of the developers of the vaccine that worked so well in monkeys. “So big pharma, who are they going to sell it to?” Dr. Geisbert added: “It takes a crisis sometimes to get people talking. ‘Ok. We’ve got to do something here.' ”

Dr. James E. Crowe Jr., director of a vaccine research center at Vanderbilt University, said that academic researchers who develop a prototype drug or vaccine that works in animals often encountered a “biotech valley of death” in which no drug company would help them cross the finish line.

Up to that point, the research may have cost a few million dollars, but tests in humans and scaling up production can cost hundreds of millions, and bringing a new vaccine all the way to market typically costs $1 billion to $1.5 billion, Dr. Crowe said. “Who’s going to pay for that?” he asked.

“People invest in order to get money back,” Dr. Crowe added.

The Ebola vaccine on which Dr. Geisbert collaborated is made from another virus, V.S.V., for vesicular stomatitis virus, which causes a mouth disease in cattle but rarely infects people. It had already been used successfully in making other vaccines.

The researchers altered V.S.V. by removing one of its genes — rendering the virus harmless — and inserting a gene from Ebola. The transplanted gene forces V.S.V. to sprout Ebola proteins on its surface. The proteins cannot cause illness, but they provoke an immune response that in monkeys, considered a good surrogate for humans, fought off the disease.

The vaccine was actually produced, in Winnipeg by the Public Health Agency of Canada. The Canadian government patented it, and 800 to 1,000 vials of the vaccine were produced. In 2010, it licensed the vaccine, known as VSV-EBOV, to NewLink Genetics, in Ames, Iowa.

The Canadian government donated the existing vials to the World Health Organization, and safety tests of the vaccine in healthy volunteers have already begun.


Almost 10 years ago...
Ebola vaccine developed that works 100% on monkeys.
Shelved before human trials due to no money in it.

And look who developed and patented it...

This does not surprise me. It does disappoint me though. If a vaccine has existed all along then why the delay in making its existence known. I know that under current law this is not criminal but it should be.
Bob DeWoody

My motto: Never do today what you can put off until tomorrow as it may not be required. This no longer applies in light of current events.
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Message 1591079 - Posted: 24 Oct 2014, 0:42:20 UTC - in response to Message 1591064.  

NYC doctor tests positive for deadly Ebola virus
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Message 1591080 - Posted: 24 Oct 2014, 0:46:50 UTC - in response to Message 1591079.  

Patient in New York City Tests Positive for Ebola

A doctor in New York City who recently returned from treating Ebola patients in Guinea tested positive for the Ebola virus Thursday, becoming the city’s first diagnosed case.

The doctor, Craig Spencer, was rushed to Bellevue Hospital on Thursday and placed in isolation while health care workers spread out across the city to trace anyone he might have come into contact with in recent days. A further test will be conducted by the federal Centers for Disease Control to confirm the initial test.

http://www.nytimes.com/2014/10/24/nyregion/craig-spencer-is-tested-for-ebola-virus-at-bellevue-hospital-in-new-york-city.html
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Message 1591081 - Posted: 24 Oct 2014, 0:50:12 UTC

I am ashamed to be a Australian our PM was the first to put his hand up to go to war , the first to turn refo's away and yet he is the last one to put his hand up to help with Ebola

I hope the Hague will bring this man to account as a independent has now formally asked the Hague to looking human rights abuses that the ABBOT gov has been doing with refugees and charge him with crimes against humanity
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Message 1591140 - Posted: 24 Oct 2014, 2:25:02 UTC

Sometime at the start of this thread i said .

"Am i being cynical that there is no vaccine ! , being Africa ?" and now we find out that Canada has one , WTF !!!

Government payed for and they have the patent , I say WTF !

2 peas in a pod Canadian PM & Australian PM !!!!..

Canada wake up you need a Royal Commission now , to get to the bottom of this .
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Message 1591154 - Posted: 24 Oct 2014, 2:58:57 UTC - in response to Message 1591149.  

Since some are so distressed at the thought of governments patenting products
of research paid for by tax-payers this article should ease your worries some...


Not distressed at the gov owning a vaccine or patent , just think why let it sit there for 10 yrs , business uses the business argument witch is fear enough , but GOV's doing this !

Aren't you a Commonwealth Country like us !

The press and Opposition would be calling for heads to rolls !
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Message 1591221 - Posted: 24 Oct 2014, 6:44:44 UTC

The situation is worsening again... Let's hope they make some work out of this:

http://www.cbc.ca/news/health/ebola-treatment-with-zmapp-cocktail-expected-in-2015-1.2781556
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Message 1591240 - Posted: 24 Oct 2014, 7:29:47 UTC

And they still let folks fly all over the world coming out of Ebola infested countrys?

Just when you thought it was ending. So much for the added screening at the airports.
It aint over yet.
Oh I forgot to add, I bet Canadas vaccine gets some human testing now.
[/quote]

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Message 1591414 - Posted: 24 Oct 2014, 15:50:44 UTC

So, just how long was Canada going to sit on the fact that a potential vaccine had already been developed and was sitting in a lab somewhere locked up waiting for it's value to go through the roof. Maybe they were getting scared that another lab was on the verge of another breakthrough.
Bob DeWoody

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Message 1591432 - Posted: 24 Oct 2014, 16:29:59 UTC - in response to Message 1591414.  

So, just how long was Canada going to sit on the fact that a potential vaccine had already been developed and was sitting in a lab somewhere locked up waiting for it's value to go through the roof. Maybe they were getting scared that another lab was on the verge of another breakthrough.


Another lab DID recently do a breakthrough.

GlaxoSmithKline.

For an article on both vaccines, might I suggest:


http://www.bidnessetc.com/27721-why-newlink-was-up-10-yesterday/

GSK’s vaccine is being developed in collaboration with the US National Institutes of Health (NIH) at a plant in Rome. It uses a combination of chimpanzee cold virus and an Ebola protein. The company has already commenced trials for the vaccine in the US, UK, and Mali.

NewLink’s VSV-EBOV is being developed in collaboration with the Public Health Agency of Canada. It has already been dispatched to the “US Walter Reed Army Institute of Research” for testing on healthy volunteers. Ms. Kieny stated that VSV-EBOV is scheduled for further testing in countries like Switzerland, Germany, and Kenya.



Note who is testing the NewLink-Canada vaccine... yep.. the US Army.

Both vaccines use genetic engineering to alter other, less lethal, viruses to appear to the body to be Ebola in order to generate an immune system response. The two use different viruses, though.
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Message 1591601 - Posted: 24 Oct 2014, 22:48:17 UTC - in response to Message 1591432.  

I'm very happy for this nurse :)

Ebola-Free Nurse Nina Pham Visits President Obama

Before returning to her "normal life" in Texas, newly Ebola-free Dallas nurse Nina Pham got a hug from President Barack Obama in the Oval Office.

Hours earlier, Pham had walked out of the National Institutes of Health Clinical Center, where she has been in isolation since Oct. 16, to a round of applause. She thanked everyone who cared for her since her Oct. 11 Ebola diagnosis, and said she would finally go home to her dog, Bentley.

http://abcnews.go.com/Health/nurse-nina-pham-contracted-ebola-now-virus-free/story?id=26406480
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Message 1591602 - Posted: 24 Oct 2014, 22:50:16 UTC - in response to Message 1591601.  

New York, New Jersey Set Up Mandatory Quarantine Requirement Amid Ebola Threat

NEW YORK (CBSNewYork/AP) — In the wake of the first confirmed Ebola virus case in New York City, the states of New York and New Jersey have set up a new screening system that goes above and beyond the guidelines already set up by federal officials.

http://newyork.cbslocal.com/2014/10/24/new-york-new-jersey-set-up-mandatory-quarantine-requirement-amid-ebola-threat/

I hope it works.
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Message 1591610 - Posted: 24 Oct 2014, 23:00:05 UTC - in response to Message 1591602.  

Ebola crisis: 'Many exposed' to infected Mali girl

Health officials fear many people may have been exposed to Mali's first Ebola victim - a two-year-old girl.

She recently arrived from Guinea, one of the worst affected countries, and has since died.

The girl showed symptoms, including a bleeding nose, while travelling on a public bus through several towns, the World Health Organization (WHO) said.

Forty-three people, including 10 health workers, who came into contact with her have been identified and isolated.

http://www.bbc.com/news/world-africa-29755443
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Message 1591618 - Posted: 24 Oct 2014, 23:19:38 UTC

Liquefies your insides, is how OEbola is described by Many.

Yet, A Nurse Gets 'it', and A Short Time Later, Looks like A Bright And Shiny Penny.

'Is' 'it' The Great Health Care or Mostly The Bodies Own Abilities To Fight, under The Right Conditions?

All The Deadly Hoopla and All I See 'is' Someone who Looks As If They Came Back from a Refreshing VERY EXPENSIVE Vacation.

And Gets A High Profile Hug.

Don't Add Up.

Yep.

I'm Not Likin' The Hysteria.

Me Neither Broheim, but Kudos to The HUwoMans Who Beat Me.

Guess For This OEbola Wormeee, Da US is A Hard Nut to Crack.

' '

May we All have a METAMORPHOSIS. REASON. GOoD JUDGEMENT and LOVE and ORDER!!!!!
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Message 1591763 - Posted: 25 Oct 2014, 5:37:29 UTC - in response to Message 1591665.  

I don't know on this one.

NEWARK (WABC) --
A health care worker arriving from Africa who was placed in mandatory quarantine as part of a new policy by the governors of New York and New Jersey has developed a fever.

The state health department said the woman had no symptoms upon arrival at Newark Liberty Airport, but on Friday night she developed the fever and is now in isolation and being evaluated at University Hospital in Newark.

http://7online.com/health/passenger-quarantined-after-treating-ebola-patients-in-africa-develops-fever/364779/
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Message boards : Politics : Ebola and Infectious diseases Part Two


 
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